| Wed, Oct 9 | vs |   Toronto Maple Leafs | SN, TVAS | W 1-0 |
| Thu, Oct 10 | @ |   Boston Bruins | TSN2, RDS | L 4-6 |
| Sat, Oct 12 | vs |   Ottawa Senators | SNE, SN1, TVAS, CITY | W 4-1 |
| Mon, Oct 14 | vs |   Pittsburgh Penguins | Prime, RDS | L 3-6 |
| Thu, Oct 17 | vs |   Los Angeles Kings | TSN2, RDS | L 1-4 |
| Sat, Oct 19 | @ |   New York Islanders | SNE, TVAS, CITY | OTL 3-4 (SO) |
| Tue, Oct 22 | vs |   New York Rangers | TSN2, RDS | L 2-7 |
| Sat, Oct 26 | vs |   St. Louis Blues | SNE, TVAS, CITY | W 5-2 |
| Sun, Oct 27 | @ |   Philadelphia Flyers | TSN2, RDS | W 4-3 |
| Tue, Oct 29 | vs |   Seattle Kraken | TSN2, RDS | L 2-8 |
| Thu, Oct 31 | @ |   Washington Capitals | TSN2, RDS | L 3-6 |
| Sat, Nov 2 | @ | Pittsburgh Penguins | SNE, TVAS, CITY · NHLN(US) | L 1-3 |
| Tue, Nov 5 | vs |   Calgary Flames | TSN2, RDS, SNW | OTL 2-3 (OT) |
| Thu, Nov 7 | @ |   New Jersey Devils | TSN2, RDS | L 3-5 |
| Sat, Nov 9 | @ | Toronto Maple Leafs | CBC, SN, TVAS | L 1-4 |
| Mon, Nov 11 | @ |   Buffalo Sabres | TSN2, RDS | W 7-5 |
| Thu, Nov 14 | @ |   Minnesota Wild | TSN2, RDS | L 0-3 |
| Sat, Nov 16 | vs |   Columbus Blue Jackets | SNE, TVAS, CITY | W 5-1 |
| Mon, Nov 18 | vs |   Edmonton Oilers | Prime, RDS | W 3-0 |
| Sat, Nov 23 | vs |   Vegas Golden Knights | SN, TVAS, CITY · NHLN(US) | L 2-6 |
| Tue, Nov 26 | vs |   Utah Mammoth | TSN2, RDS | OTL 2-3 (OT) |
| Wed, Nov 27 | @ | Columbus Blue Jackets | SNE, RDS | W 4-3 (OT) |
| Sat, Nov 30 | @ | New York Rangers | TSN2, RDS · NHLN(US) | L 3-4 |
| Sun, Dec 1 | @ | Boston Bruins | SN, RDS | L 3-6 |
| Tue, Dec 3 | vs | New York Islanders | TSN2, RDS | W 2-1 (OT) |
| Thu, Dec 5 | vs |   Nashville Predators | TSN2, RDS | W 3-0 |
| Sat, Dec 7 | vs | Washington Capitals | SNE, TVAS, CITY | L 2-4 |
| Mon, Dec 9 | vs |   Anaheim Ducks | Prime, RDS | W 3-2 (SO) |
| Thu, Dec 12 | vs | Pittsburgh Penguins | TSN2, RDS | L 2-9 |
| Sat, Dec 14 | @ |   Winnipeg Jets | SN, TVAS, CITY | L 2-4 |
| Tue, Dec 17 | vs | Buffalo Sabres | TSN2, RDS | W 6-1 |
| Fri, Dec 20 | @ |   Detroit Red Wings | TSN2, RDS | W 4-3 |
| Sat, Dec 21 | vs | Detroit Red Wings | SNE, TVAS, CITY · NHLN(US) | W 5-1 |
| Mon, Dec 23 | @ | Columbus Blue Jackets | TSN2, RDS | L 4-5 |
| Sat, Dec 28 | @ |   Florida Panthers | TSN2, RDS | W 4-0 |
| Sun, Dec 29 | @ |   Tampa Bay Lightning | TSN2, RDS | W 5-2 |
| Tue, Dec 31 | @ | Vegas Golden Knights | TSN2, RDS | W 3-2 |
| Fri, Jan 3 | @ |   Chicago Blackhawks | TSN2, RDS | L 2-4 |
| Sat, Jan 4 | @ |   Colorado Avalanche | SNE, TVAS, CITY | W 2-1 (SO) |
| Mon, Jan 6 | vs |   Vancouver Canucks | Prime, RDS | W 5-4 (OT) |
| Fri, Jan 10 | @ | Washington Capitals | TSN2, RDS | W 3-2 (OT) |
| Sat, Jan 11 | vs |   Dallas Stars | SNE, TVAS, CITY | OTL 1-2 (SO) |
| Tue, Jan 14 | @ | Utah Mammoth | TSN2, RDS | W 5-3 |
| Thu, Jan 16 | @ | Dallas Stars | TSN2, RDS | W 3-1 |
| Sat, Jan 18 | vs | Toronto Maple Leafs | SN, CBC, TVAS · NHLN(US) | L 3-7 |
| Sun, Jan 19 | vs | New York Rangers | TSN2, RDS · NHLN(US) | W 5-4 (OT) |
| Tue, Jan 21 | vs | Tampa Bay Lightning | TSN2, RDS | W 3-2 |
| Thu, Jan 23 | @ | Detroit Red Wings | TSN2, RDS | L 2-4 |
| Sat, Jan 25 | vs | New Jersey Devils | SNE, TVAS, CITY · NHLN(US) | OTL 3-4 (OT) |
| Tue, Jan 28 | vs | Winnipeg Jets | TSN2, RDS, TSN3 | L 1-4 |
| Thu, Jan 30 | vs | Minnesota Wild | TSN2, RDS | L 0-4 |
| Sun, Feb 2 | @ | Anaheim Ducks | TSN2, RDS | L 2-3 |
| Tue, Feb 4 | @ |   San Jose Sharks | TSN2, RDS | W 4-3 |
| Wed, Feb 5 | @ | Los Angeles Kings | TSN2, RDS | L 3-6 |
| Sat, Feb 8 | vs | New Jersey Devils | TSN2, RDS | L 0-4 |
| Sun, Feb 9 | vs | Tampa Bay Lightning | TSN2, RDS · NHLN(US) | L 3-5 |
| Sat, Feb 22 | @ | Ottawa Senators | SNE, TVAS, CITY | W 5-2 |
| Tue, Feb 25 | vs |   Carolina Hurricanes | TSN2, RDS | W 4-0 |
| Thu, Feb 27 | vs | San Jose Sharks | TSN2, RDS | W 4-3 (OT) |
| Sat, Mar 1 | @ | Buffalo Sabres | SNE, TVAS, CITY | W 4-2 |
| Mon, Mar 3 | vs | Buffalo Sabres | TSN2, RDS | W 4-3 (OT) |
| Thu, Mar 6 | @ | Edmonton Oilers | TSN2, RDS, SNW | OTL 2-3 (OT) |
| Sat, Mar 8 | @ | Calgary Flames | SN, TVAS, CITY | L 0-1 |
| Tue, Mar 11 | @ | Vancouver Canucks | TSN2, RDS, SNP | W 4-2 |
| Wed, Mar 12 | @ | Seattle Kraken | TSN2, RDS | OTL 4-5 (OT) |
| Sat, Mar 15 | vs | Florida Panthers | SNE, TVAS, CITY · NHLN(US) | W 3-1 |
| Tue, Mar 18 | vs | Ottawa Senators | TSN2, RDS, TSN5 | W 6-3 |
| Thu, Mar 20 | @ | New York Islanders | TSN2, RDS | OTL 3-4 (OT) |
| Sat, Mar 22 | vs | Colorado Avalanche | SNE, TVAS, CITY | OTL 4-5 (SO) |
| Tue, Mar 25 | @ | St. Louis Blues | TSN2, RDS | L 1-6 |
| Thu, Mar 27 | @ | Philadelphia Flyers | TSN2, RDS | L 4-6 |
| Fri, Mar 28 | @ | Carolina Hurricanes | TSN2, RDS | L 1-4 |
| Sun, Mar 30 | @ | Florida Panthers | TSN2, RDS · NHLN(US) | W 4-2 |
| Tue, Apr 1 | vs | Florida Panthers | TSN2, RDS | W 3-2 (OT) |
| Thu, Apr 3 | vs | Boston Bruins | SN, RDS | W 4-1 |
| Sat, Apr 5 | vs | Philadelphia Flyers | SNE, TVAS, CITY | W 3-2 |
| Sun, Apr 6 | @ | Nashville Predators | TSN2, RDS | W 2-1 |
| Tue, Apr 8 | vs | Detroit Red Wings | TSN2, RDS | W 4-1 |
| Fri, Apr 11 | @ | Ottawa Senators | SN, SN1, RDS | L 2-5 |
| Sat, Apr 12 | @ | Toronto Maple Leafs | SN, CBC, TVAS | OTL 0-1 (OT) |
| Mon, Apr 14 | vs | Chicago Blackhawks | Prime, RDS | OTL 3-4 (SO) |
| Wed, Apr 16 | vs | Carolina Hurricanes | SN, SN1, RDS | W 4-2 |
| Mon, Apr 21 | @ | Washington Capitals | SN, TVAS · ESPN(US) | OTL 2-3 (OT) |
| Wed, Apr 23 | @ | Washington Capitals | CBC, SN, TVAS · ESPN(US) | L 1-3 |
| Fri, Apr 25 | vs | Washington Capitals | CBC, SN, TVAS · TNT, truTV, MAX(US) | W 6-3 |
| Sun, Apr 27 | vs | Washington Capitals | CBC, SN, TVAS · TBS, truTV, MAX(US) | L 2-5 |
| Wed, Apr 30 | @ | Washington Capitals | SN, CBC, TVAS · ESPN(US) | L 1-4 |
