| Tue, Oct 8 | vs |   St. Louis Blues | ESPN+, ESPN · SN360, TVAS(CA) | L 2-3 |
| Sat, Oct 12 | @ |   Minnesota Wild | | W 5-4 (SO) |
| Sun, Oct 13 | @ |   Dallas Stars | | L 0-2 |
| Tue, Oct 15 | @ |   Nashville Predators | | W 7-3 |
| Thu, Oct 17 | vs |   Philadelphia Flyers | | W 6-4 |
| Sat, Oct 19 | vs |   Calgary Flames | CBC, SN, CITY | W 2-1 (OT) |
| Tue, Oct 22 | vs |   Colorado Avalanche | ESPN+, ESPN | L 2-3 |
| Thu, Oct 24 | vs |   Winnipeg Jets | TVAS, TSN3 | OTL 3-4 (OT) |
| Sat, Oct 26 | vs |   Carolina Hurricanes | | L 1-4 |
| Tue, Oct 29 | @ |   Montreal Canadiens | TSN2, RDS | W 8-2 |
| Thu, Oct 31 | @ |   Toronto Maple Leafs | TSN4 | L 1-4 |
| Sat, Nov 2 | @ |   Ottawa Senators | SN1 | L 0-3 |
| Sun, Nov 3 | @ |   Boston Bruins | SN, SN1, TVAS | L 0-2 |
| Tue, Nov 5 | @ | Colorado Avalanche | SN1 | L 3-6 |
| Fri, Nov 8 | vs |   Vegas Golden Knights | SN (JIP), TVAS | W 4-3 (OT) |
| Tue, Nov 12 | vs |   Columbus Blue Jackets | | W 5-2 |
| Thu, Nov 14 | vs |   Chicago Blackhawks | SN, SN1 | W 3-1 |
| Sat, Nov 16 | vs |   New York Islanders | SN | W 3-2 |
| Sun, Nov 17 | vs |   New York Rangers | | L 0-2 |
| Wed, Nov 20 | vs | Nashville Predators | TNT, truTV, MAX · TVAS(CA) | W 3-0 |
| Sat, Nov 23 | @ |   Los Angeles Kings | SN | L 1-2 |
| Mon, Nov 25 | @ |   Anaheim Ducks | | W 3-2 |
| Wed, Nov 27 | vs | Anaheim Ducks | | L 2-5 |
| Fri, Nov 29 | @ |   San Jose Sharks | | L 5-8 |
| Sat, Nov 30 | vs | San Jose Sharks | | L 2-4 |
| Tue, Dec 3 | @ | Carolina Hurricanes | | W 4-2 |
| Thu, Dec 5 | @ | New York Islanders | ESPN+, HULU | W 5-2 |
| Fri, Dec 6 | @ |   New Jersey Devils | | L 2-3 |
| Sun, Dec 8 | @ | New York Rangers | NHLN · SN, TVAS(CA) | W 7-5 |
| Tue, Dec 10 | vs |   Florida Panthers | | OTL 1-2 (SO) |
| Thu, Dec 12 | vs | Boston Bruins | SN | W 5-1 |
| Sat, Dec 14 | vs |   Tampa Bay Lightning | | L 1-5 |
| Tue, Dec 17 | vs | Ottawa Senators | TSN5, RDS | L 0-3 |
| Thu, Dec 19 | @ | Chicago Blackhawks | | L 1-3 |
| Sat, Dec 21 | @ | Vegas Golden Knights | | L 2-6 |
| Sun, Dec 22 | @ | Colorado Avalanche | NHLN · SN(CA) | L 2-5 |
| Sat, Dec 28 | @ |   Vancouver Canucks | SNP | W 5-4 (OT) |
| Mon, Dec 30 | vs |   Utah Mammoth | | W 5-2 |
| Thu, Jan 2 | vs | Vancouver Canucks | SNP | OTL 3-4 (SO) |
| Sat, Jan 4 | vs |   Edmonton Oilers | SN, CBC, SN360 | L 2-4 |
| Mon, Jan 6 | vs | New Jersey Devils | | L 2-3 |
| Thu, Jan 9 | @ | Columbus Blue Jackets | | L 2-6 |
| Sat, Jan 11 | @ |   Buffalo Sabres | SN | W 6-2 |
| Sun, Jan 12 | @ |   Detroit Red Wings | NHLN · SN(CA) | L 2-6 |
| Tue, Jan 14 | @ |   Pittsburgh Penguins | | W 4-2 |
| Thu, Jan 16 | @ | Winnipeg Jets | TSN3 | L 1-2 |
| Sat, Jan 18 | vs | Los Angeles Kings | | W 4-2 |
| Mon, Jan 20 | vs | Buffalo Sabres | TVAS | W 6-4 |
| Thu, Jan 23 | vs |   Washington Capitals | SN | L 0-3 |
| Sat, Jan 25 | vs | Pittsburgh Penguins | | W 4-1 |
| Mon, Jan 27 | @ | Edmonton Oilers | TVAS, SNW | L 2-4 |
| Tue, Jan 28 | vs | Anaheim Ducks | | L 4-6 |
| Thu, Jan 30 | vs | San Jose Sharks | ESPN | W 6-2 |
| Sun, Feb 2 | vs | Calgary Flames | SN, SN1 | L 2-3 |
| Tue, Feb 4 | vs | Detroit Red Wings | | OTL 4-5 (SO) |
| Thu, Feb 6 | vs | Toronto Maple Leafs | TVAS, TSN4 · ESPN+, HULU(US) | L 1-3 |
| Sat, Feb 8 | @ | Calgary Flames | CBC, SN, SN1, TVAS, CITY | W 3-2 (OT) |
| Sat, Feb 22 | @ | Florida Panthers | | W 2-1 |
| Sun, Feb 23 | @ | Tampa Bay Lightning | | L 1-4 |
| Tue, Feb 25 | @ | St. Louis Blues | | L 2-7 |
| Sat, Mar 1 | vs | Vancouver Canucks | CBC, SN, SN1, CITY | W 6-3 |
| Tue, Mar 4 | vs | Minnesota Wild | | L 3-4 |
| Thu, Mar 6 | @ | Nashville Predators | | L 3-5 |
| Sat, Mar 8 | @ | Philadelphia Flyers | ESPN+, ABC · SN1(CA) | W 4-1 |
| Sun, Mar 9 | @ | Washington Capitals | SN360, SN (JIP) | L 2-4 |
| Wed, Mar 12 | vs | Montreal Canadiens | TSN2, RDS | W 5-4 (OT) |
| Fri, Mar 14 | vs | Utah Mammoth | | W 4-2 |
| Sun, Mar 16 | vs | Winnipeg Jets | TSN3 | OTL 2-3 (OT) |
| Tue, Mar 18 | @ | Chicago Blackhawks | | W 6-2 |
| Wed, Mar 19 | @ | Minnesota Wild | TNT, MAX · SN360, TVAS(CA) | L 0-4 |
| Sat, Mar 22 | @ | Edmonton Oilers | CBC, SN, SN1, SN360, CITY | L 4-5 |
| Tue, Mar 25 | @ | Calgary Flames | SNW | OTL 3-4 (OT) |
| Thu, Mar 27 | vs | Edmonton Oilers | SN, SN1 | W 6-1 |
| Sat, Mar 29 | vs | Dallas Stars | | L 1-5 |
| Mon, Mar 31 | vs | Dallas Stars | TVAS | L 1-3 |
| Wed, Apr 2 | @ | Vancouver Canucks | TVAS2, SNP | W 5-0 |
| Sat, Apr 5 | @ | San Jose Sharks | | W 5-1 |
| Mon, Apr 7 | @ | Los Angeles Kings | | W 2-1 |
| Tue, Apr 8 | @ | Utah Mammoth | | L 1-7 |
| Thu, Apr 10 | @ | Vegas Golden Knights | TVAS | L 1-2 |
| Sat, Apr 12 | vs | St. Louis Blues | | W 4-3 (SO) |
| Tue, Apr 15 | vs | Los Angeles Kings | ESPN · SN, SN360(CA) | L 5-6 |
