| Tue, Oct 10 | @ |   Vegas Golden Knights | ESPN+, ESPN · SN, TVAS(CA) | L 1-4 |
| Thu, Oct 12 | @ |   Nashville Predators | | L 0-3 |
| Sat, Oct 14 | @ |   St. Louis Blues | | OTL 1-2 (SO) |
| Tue, Oct 17 | vs |   Colorado Avalanche | ESPN · SNP(CA) | L 1-4 |
| Thu, Oct 19 | vs |   Carolina Hurricanes | | W 7-4 |
| Sat, Oct 21 | vs |   New York Rangers | | L 1-4 |
| Tue, Oct 24 | @ |   Detroit Red Wings | | W 5-4 (OT) |
| Thu, Oct 26 | @ | Carolina Hurricanes | | OTL 2-3 (OT) |
| Sat, Oct 28 | @ |   Florida Panthers | | L 2-3 |
| Mon, Oct 30 | @ |   Tampa Bay Lightning | | W 4-3 (OT) |
| Thu, Nov 2 | vs | Nashville Predators | SN | W 4-2 |
| Sat, Nov 4 | vs |   Calgary Flames | SN, SN1, CITY | L 3-6 |
| Tue, Nov 7 | @ |   ARI | | OTL 3-4 (SO) |
| Thu, Nov 9 | @ | Colorado Avalanche | TVAS | W 4-3 |
| Sat, Nov 11 | vs |   Edmonton Oilers | CBC, SN, SN1, TVAS2, CITY | L 1-4 |
| Mon, Nov 13 | vs | Colorado Avalanche | TVAS | L 1-5 |
| Wed, Nov 15 | @ | Edmonton Oilers | SN, SN360 | OTL 3-4 (OT) |
| Thu, Nov 16 | vs |   New York Islanders | | W 4-3 (SO) |
| Sat, Nov 18 | @ |   Vancouver Canucks | CBC, SN, SN1, SN360, TVAS2, CITY | W 4-3 |
| Mon, Nov 20 | vs | Calgary Flames | SN, SN1 | OTL 3-4 (OT) |
| Wed, Nov 22 | vs |   San Jose Sharks | | W 7-1 |
| Fri, Nov 24 | vs | Vancouver Canucks | SNP | L 1-5 |
| Tue, Nov 28 | @ |   Chicago Blackhawks | TVAS-D | L 3-4 |
| Thu, Nov 30 | @ |   Toronto Maple Leafs | TSN4 | OTL 3-4 (SO) |
| Sat, Dec 2 | @ |   Ottawa Senators | SN1, TVAS2 | L 0-2 |
| Mon, Dec 4 | @ |   Montreal Canadiens | SN, SN1, RDS | L 2-4 |
| Thu, Dec 7 | vs |   New Jersey Devils | ESPN | L 1-2 |
| Sat, Dec 9 | vs | Tampa Bay Lightning | TVAS2 | OTL 3-4 (OT) |
| Sun, Dec 10 | vs |   Minnesota Wild | | L 0-3 |
| Tue, Dec 12 | vs | Florida Panthers | | W 4-0 |
| Thu, Dec 14 | vs | Chicago Blackhawks | TVAS | W 7-1 |
| Sat, Dec 16 | vs |   Los Angeles Kings | | OTL 2-3 (SO) |
| Mon, Dec 18 | @ |   Dallas Stars | NHLN | OTL 3-4 (OT) |
| Wed, Dec 20 | @ | Los Angeles Kings | TNT, MAX · TVAS(CA) | W 2-1 |
| Sat, Dec 23 | @ |   Anaheim Ducks | | W 3-2 |
| Wed, Dec 27 | @ | Calgary Flames | SNW, SN360, TVAS | W 2-1 |
| Fri, Dec 29 | vs |   Philadelphia Flyers | | W 2-1 (OT) |
| Mon, Jan 1 | vs | Vegas Golden Knights | TNT, truTV, MAX · SN, TVAS(CA) | W 3-0 |
| Thu, Jan 4 | vs | Ottawa Senators | TSN5, RDS | W 4-1 |
| Tue, Jan 9 | @ |   Buffalo Sabres | | W 5-2 |
| Thu, Jan 11 | @ |   Washington Capitals | | W 4-1 |
| Sat, Jan 13 | @ |   Columbus Blue Jackets | | W 7-4 |
| Mon, Jan 15 | @ |   Pittsburgh Penguins | | L 0-3 |
| Tue, Jan 16 | @ | New York Rangers | | L 2-5 |
| Thu, Jan 18 | @ | Edmonton Oilers | SN1 | L 2-4 |
| Sun, Jan 21 | vs | Toronto Maple Leafs | TVAS, SNO | L 1-3 |
| Wed, Jan 24 | vs | Chicago Blackhawks | TNT, MAX · SN(CA) | W 6-2 |
| Fri, Jan 26 | vs | St. Louis Blues | SN | OTL 3-4 (OT) |
| Sun, Jan 28 | vs | Columbus Blue Jackets | SN | W 4-2 |
| Tue, Jan 30 | @ | San Jose Sharks | SN, SN360, TVAS | L 0-2 |
| Sat, Feb 10 | @ | Philadelphia Flyers | ESPN+, HULU | L 2-3 |
| Mon, Feb 12 | @ | New Jersey Devils | | L 1-3 |
| Tue, Feb 13 | @ | New York Islanders | | W 2-1 (SO) |
| Thu, Feb 15 | @ |   Boston Bruins | SN | W 4-1 |
| Mon, Feb 19 | vs | Detroit Red Wings | ESPN | OTL 3-4 (OT) |
| Thu, Feb 22 | vs | Vancouver Canucks | SNP | W 5-2 |
| Sat, Feb 24 | vs | Minnesota Wild | | L 2-5 |
| Mon, Feb 26 | vs | Boston Bruins | | W 4-3 (SO) |
| Thu, Feb 29 | vs | Pittsburgh Penguins | SN | W 2-0 |
| Sat, Mar 2 | vs | Edmonton Oilers | SN | L 1-2 |
| Mon, Mar 4 | @ | Calgary Flames | SNW, SN1, TVAS | W 4-2 |
| Tue, Mar 5 | @ |   Winnipeg Jets | TSN3 | W 4-3 |
| Fri, Mar 8 | vs | Winnipeg Jets | TSN3 | L 0-3 |
| Tue, Mar 12 | vs | Vegas Golden Knights | SN | OTL 4-5 (OT) |
| Thu, Mar 14 | vs | Washington Capitals | SN | L 1-2 |
| Sat, Mar 16 | vs | Nashville Predators | | L 1-4 |
| Mon, Mar 18 | vs | Buffalo Sabres | | L 2-6 |
| Thu, Mar 21 | @ | Vegas Golden Knights | ESPN | L 1-3 |
| Fri, Mar 22 | @ | ARI | SN, TVAS | OTL 1-2 (OT) |
| Sun, Mar 24 | vs | Montreal Canadiens | TSN2, RDS | L 1-5 |
| Tue, Mar 26 | vs | Anaheim Ducks | | W 4-0 |
| Thu, Mar 28 | vs | Anaheim Ducks | | W 4-2 |
| Sat, Mar 30 | vs | Dallas Stars | | L 0-3 |
| Mon, Apr 1 | @ | San Jose Sharks | | W 4-2 |
| Wed, Apr 3 | @ | Los Angeles Kings | TVAS | L 2-5 |
| Fri, Apr 5 | @ | Anaheim Ducks | | W 3-1 |
| Tue, Apr 9 | vs | ARI | | W 5-0 |
| Thu, Apr 11 | vs | San Jose Sharks | SN | L 1-3 |
| Sat, Apr 13 | @ | Dallas Stars | ESPN+, ABC · SN360(CA) | L 1-3 |
| Sun, Apr 14 | @ | St. Louis Blues | TNT, MAX | L 1-4 |
| Tue, Apr 16 | @ | Winnipeg Jets | TSN3 | L 3-4 |
| Thu, Apr 18 | @ | Minnesota Wild | ESPN | W 4-3 |
