| Thu, Oct 9 | vs |   New York Rangers | ESPN+, MSG-B, MSG | L 0-4 |
| Sat, Oct 11 | @ |   Boston Bruins | ESPN+, MSG-B, NESN | L 1-3 |
| Mon, Oct 13 | vs |   Colorado Avalanche | ESPN+, MSG-B, ALT | L 1-3 |
| Wed, Oct 15 | vs |   Ottawa Senators | ESPN+, MSG-B | W 8-4 |
| Sat, Oct 18 | vs |   Florida Panthers | ESPN+, MSG-B, SCRIPPS | W 3-0 |
| Mon, Oct 20 | @ |   Montreal Canadiens | ESPN+, MSG-B | L 2-4 |
| Wed, Oct 22 | vs |   Detroit Red Wings | HBO MAX, TNT, truTV, FDSNDETX | W 4-2 |
| Fri, Oct 24 | vs |   Toronto Maple Leafs | ESPN+, HULU | W 5-3 |
| Sat, Oct 25 | @ | Toronto Maple Leafs | ESPN+, MSG-B | OTL 3-4 (OT) |
| Tue, Oct 28 | vs |   Columbus Blue Jackets | ESPN+, MSG-B, FDSNOH | OTL 3-4 (OT) |
| Thu, Oct 30 | @ | Boston Bruins | ESPN+, MSG-B, NESN | OTL 3-4 (OT) |
| Sat, Nov 1 | vs |   Washington Capitals | ESPN+, MSG-B, MNMT2 | W 4-3 (SO) |
| Tue, Nov 4 | vs |   Utah Mammoth | ESPN+, MSG-B, Utah16 | OTL 1-2 (OT) |
| Thu, Nov 6 | vs |   St. Louis Blues | ESPN+, MSG-B, FDSNMW | L 0-3 |
| Sat, Nov 8 | @ |   Carolina Hurricanes | ESPN+, MSG-B, FDSNSO | L 3-6 |
| Wed, Nov 12 | @ | Utah Mammoth | ESPN+, MSG-B, Utah16 | L 2-5 |
| Thu, Nov 13 | @ | Colorado Avalanche | ESPN+, MSG-B, KUSA, ALT, KTVD | L 3-6 |
| Sat, Nov 15 | @ | Detroit Red Wings | ESPN+, MSG-B, FDSNDET | W 5-4 (OT) |
| Mon, Nov 17 | vs |   Edmonton Oilers | ESPN+, MSG-B | W 5-1 |
| Wed, Nov 19 | vs |   Calgary Flames | ESPN+, MSG-B | L 2-6 |
| Fri, Nov 21 | vs |   Chicago Blackhawks | ESPN+, MSG-B, CHSN | W 9-3 |
| Sun, Nov 23 | vs | Carolina Hurricanes | NHLN, MSG-B, FDSNSO | W 4-1 |
| Wed, Nov 26 | @ |   Pittsburgh Penguins | ESPN+, MSG-B, SN-PIT | L 2-4 |
| Fri, Nov 28 | vs |   New Jersey Devils | ESPN+, MSG-B, MSG | L 0-5 |
| Sat, Nov 29 | @ |   Minnesota Wild | ESPN+, MSG-B, FDSNNOX, FDSNWIX | W 3-2 (SO) |
| Mon, Dec 1 | vs |   Winnipeg Jets | ESPN+, MSG-B | W 5-1 |
| Wed, Dec 3 | @ |   Philadelphia Flyers | HBO MAX, TNT | L 2-5 |
| Fri, Dec 5 | @ | Winnipeg Jets | ESPN+, MSG-B | L 1-4 |
| Mon, Dec 8 | @ | Calgary Flames | ESPN+, MSG-B | L 4-7 |
| Tue, Dec 9 | @ | Edmonton Oilers | ESPN+, MSG-B | W 4-3 (OT) |
| Thu, Dec 11 | @ |   Vancouver Canucks | ESPN+, MSG-B | W 3-2 |
| Sun, Dec 14 | @ |   Seattle Kraken | ESPN+, MSG-B, KHN/Prime, KONG | W 3-1 |
| Thu, Dec 18 | vs | Philadelphia Flyers | ESPN+, HULU | W 5-3 |
| Sat, Dec 20 | vs |   New York Islanders | ESPN+, MSG-B, MSGSN | W 3-2 (SO) |
| Sun, Dec 21 | @ | New Jersey Devils | ESPN+, MSG-B, MSGSN | W 3-1 |
| Tue, Dec 23 | @ | Ottawa Senators | ESPN+, MSG-B | W 3-2 (OT) |
| Sat, Dec 27 | vs | Boston Bruins | ESPN+, MSG-B, NESN | W 4-1 |
| Mon, Dec 29 | @ | St. Louis Blues | ESPN+, MSG-B, FDSNMW | W 4-2 |
| Wed, Dec 31 | @ |   Dallas Stars | ESPN+, Victory+, MSG-B | W 4-1 |
| Sat, Jan 3 | @ | Columbus Blue Jackets | ESPN+, MSG-B, FDSNOH | L 1-5 |
| Tue, Jan 6 | vs | Vancouver Canucks | ESPN+, MSG-B | W 5-3 |
| Thu, Jan 8 | @ | New York Rangers | ESPN+, MSG-B, MSG | W 5-2 |
| Sat, Jan 10 | vs |   Anaheim Ducks | ESPN+, Victory+, MSG-B, KCOP-13 | W 5-3 |
| Mon, Jan 12 | vs | Florida Panthers | ESPN+, MSG-B, SCRIPPS | L 3-4 |
| Wed, Jan 14 | vs | Philadelphia Flyers | HBO MAX, TNT, truTV | W 5-2 |
| Thu, Jan 15 | vs | Montreal Canadiens | ESPN+, MSG-B | W 5-3 |
| Sat, Jan 17 | vs | Minnesota Wild | NHLN, MSG-B, FDSNNO, FDSNWI | OTL 4-5 (OT) |
| Mon, Jan 19 | @ | Carolina Hurricanes | HBO MAX, TNT, truTV | L 1-2 |
| Tue, Jan 20 | @ |   Nashville Predators | ESPN+, MSG-B, FDSNSO | W 5-3 |
| Thu, Jan 22 | @ | Montreal Canadiens | ESPN+, MSG-B | W 4-2 |
| Sat, Jan 24 | @ | New York Islanders | ESPN+, MSG-B, MSGSN | W 5-0 |
| Tue, Jan 27 | @ | Toronto Maple Leafs | ESPN+, MSG-B | W 7-4 |
| Thu, Jan 29 | vs |   Los Angeles Kings | ESPN+, MSG-B, FDSNW | W 4-1 |
| Sat, Jan 31 | vs | Montreal Canadiens | NHLN, MSG-B | L 2-4 |
| Mon, Feb 2 | @ | Florida Panthers | ESPN+, MSG-B, SCRIPPS | W 5-3 |
| Tue, Feb 3 | @ |   Tampa Bay Lightning | ESPN+, HULU | OTL 3-4 (OT) |
| Thu, Feb 5 | vs | Pittsburgh Penguins | ESPN+, MSG-B, SN-PIT | L 2-5 |
| Wed, Feb 25 | @ | New Jersey Devils | ESPN+, MSG-B, MSGSN | W 2-1 |
| Fri, Feb 27 | @ | Florida Panthers | ESPN+, MSG-B, SCRIPPS | W 3-2 |
| Sat, Feb 28 | @ | Tampa Bay Lightning | ESPN+, MSG-B, The Spot | W 6-2 |
| Tue, Mar 3 | vs |   Vegas Golden Knights | ESPN+, MSG-B, SCRIPPS | W 3-2 |
| Thu, Mar 5 | @ | Pittsburgh Penguins | ESPN | W 5-1 |
| Sat, Mar 7 | vs | Nashville Predators | ESPN+, MSG-B, FDSNSO | W 3-2 |
| Sun, Mar 8 | vs | Tampa Bay Lightning | ESPN+, MSG-B, The Spot | W 8-7 |
| Tue, Mar 10 | vs |   San Jose Sharks | ESPN+, MSG-B, NBCSCA | W 6-3 |
| Thu, Mar 12 | vs | Washington Capitals | ESPN+, MSG-B, MNMT2 | L 1-2 |
| Sat, Mar 14 | vs | Toronto Maple Leafs | NHLN, MSG-B | W 3-2 (SO) |
| Tue, Mar 17 | @ | Vegas Golden Knights | ESPN+, MSG-B, SCRIPPS | W 2-0 |
| Thu, Mar 19 | @ | San Jose Sharks | ESPN+, MSG-B, NBCSCA | W 5-0 |
| Sat, Mar 21 | @ | Los Angeles Kings | ESPN+, MSG-B, FDSNW | W 4-1 |
| Sun, Mar 22 | @ | Anaheim Ducks | ESPN+, Victory+, MSG-B, KTTV | OTL 5-6 (OT) |
| Wed, Mar 25 | vs | Boston Bruins | HBO MAX, TNT, truTV, NESN | OTL 3-4 (OT) |
| Fri, Mar 27 | vs | Detroit Red Wings | NHLN, MSG-B, FDSNDET | L 2-5 |
| Sat, Mar 28 | vs | Seattle Kraken | ESPN+, MSG-B, KHN/Prime, KONG | W 3-2 (SO) |
| Tue, Mar 31 | vs | New York Islanders | ESPN+, MSG-B, MSGSN2 | W 4-3 |
| Thu, Apr 2 | @ | Ottawa Senators | ESPN+, MSG-B | L 1-4 |
| Sat, Apr 4 | @ | Washington Capitals | ESPN+, MSG-B, MNMT | L 2-6 |
| Mon, Apr 6 | vs | Tampa Bay Lightning | NHLN, MSG-B, The Spot | W 4-2 |
| Wed, Apr 8 | @ | New York Rangers | HBO MAX, TNT, truTV, MSG | W 5-3 |
| Thu, Apr 9 | vs | Columbus Blue Jackets | ESPN+, MSG-B, FDSNOH | W 5-0 |
| Mon, Apr 13 | @ | Chicago Blackhawks | ESPN+, MSG-B, CHSN | W 5-1 |
| Wed, Apr 15 | vs | Dallas Stars | HBO MAX, Victory+, TNT, truTV, MORE27 | OTL 3-4 (SO) |
| Sun, Apr 19 | vs | Boston Bruins | ESPN, MSG-B, NESN | W 4-3 |
| Tue, Apr 21 | vs | Boston Bruins | ESPN, MSG-B, NESN | L 2-4 |
| Thu, Apr 23 | @ | Boston Bruins | HBO MAX, TNT, truTV, MSG-B, NESN | W 3-1 |
| Sun, Apr 26 | @ | Boston Bruins | HBO MAX, TNT, truTV, MSG-B, NESN | W 6-1 |
| Tue, Apr 28 | vs | Boston Bruins | HBO MAX, TNT, truTV, MSG-B, NESN | OTL 1-2 (OT) |
| Fri, May 1 | @ | Boston Bruins | ESPN, MSG-B, NESN | W 4-1 |
| Wed, May 6 | vs | Montreal Canadiens | HBO MAX, TNT, truTV | W 4-2 |
| Fri, May 8 | vs | Montreal Canadiens | HBO MAX, TNT | L 1-5 |
| Sun, May 10 | @ | Montreal Canadiens | ESPN | L 2-6 |
| Tue, May 12 | @ | Montreal Canadiens | ESPN | W 3-2 |
| Thu, May 14 | vs | Montreal Canadiens | HBO MAX, TNT, truTV | L 3-6 |
| Sat, May 16 | @ | Montreal Canadiens | ABC | W 8-3 |
| Mon, May 18 | vs | Montreal Canadiens | ESPN | OTL 2-3 (OT) |
