| Wed, Oct 11 | @ |   Calgary Flames | SNW | L 3-5 |
| Sat, Oct 14 | vs |   Florida Panthers | TSN3 | W 6-4 |
| Tue, Oct 17 | vs |   Los Angeles Kings | TVAS, TSN3 | L 1-5 |
| Thu, Oct 19 | vs |   Vegas Golden Knights | TSN3 | L 3-5 |
| Sat, Oct 21 | @ |   Edmonton Oilers | CBC, SN, TVAS2, CITY | W 3-2 (OT) |
| Tue, Oct 24 | vs |   St. Louis Blues | TSN3 | W 4-2 |
| Thu, Oct 26 | @ |   Detroit Red Wings | TSN3 | W 4-1 |
| Sat, Oct 28 | @ |   Montreal Canadiens | TVAS, CITY | OTL 3-4 (SO) |
| Mon, Oct 30 | vs |   New York Rangers | SN1 | OTL 2-3 (OT) |
| Thu, Nov 2 | @ | Vegas Golden Knights | TSN3 | L 2-5 |
| Sat, Nov 4 | @ |   ARI | TSN3 | W 5-3 |
| Tue, Nov 7 | @ | St. Louis Blues | TSN3 | W 5-2 |
| Thu, Nov 9 | vs |   Nashville Predators | TSN3 | W 6-3 |
| Sat, Nov 11 | vs |   Dallas Stars | TSN3 | L 2-3 |
| Tue, Nov 14 | vs |   New Jersey Devils | TSN3 | W 6-3 |
| Fri, Nov 17 | vs |   Buffalo Sabres | TSN3 · NHLN(US) | W 3-2 |
| Sat, Nov 18 | vs | ARI | SN1, SN360 | W 5-2 |
| Wed, Nov 22 | @ |   Tampa Bay Lightning | SNW | W 3-2 (OT) |
| Fri, Nov 24 | @ | Florida Panthers | TSN3 | W 3-0 |
| Sun, Nov 26 | @ | Nashville Predators | TSN3 | L 2-3 |
| Tue, Nov 28 | vs | Dallas Stars | TSN3 | L 0-2 |
| Thu, Nov 30 | vs | Edmonton Oilers | TSN3, SNW | L 1-3 |
| Sat, Dec 2 | vs |   Chicago Blackhawks | TVAS, TSN3 | W 3-1 |
| Mon, Dec 4 | vs |   Carolina Hurricanes | SNW | W 2-1 |
| Thu, Dec 7 | @ |   Colorado Avalanche | TVAS, TSN3 | W 4-2 |
| Sun, Dec 10 | @ |   Anaheim Ducks | TSN3 | W 4-2 |
| Tue, Dec 12 | @ |   San Jose Sharks | TSN3 | L 1-2 |
| Wed, Dec 13 | @ | Los Angeles Kings | TVAS, TSN3 | W 5-2 |
| Sat, Dec 16 | vs | Colorado Avalanche | SNW, SN360 | W 6-2 |
| Mon, Dec 18 | vs | Montreal Canadiens | SN, RDS | OTL 2-3 (OT) |
| Wed, Dec 20 | vs | Detroit Red Wings | SN | W 5-2 |
| Fri, Dec 22 | vs |   Boston Bruins | TSN3 | W 5-1 |
| Wed, Dec 27 | @ | Chicago Blackhawks | TSN3 | OTL 1-2 (OT) |
| Sat, Dec 30 | vs |   Minnesota Wild | TSN3 | W 4-2 |
| Sun, Dec 31 | @ | Minnesota Wild | TSN3 | W 3-2 |
| Tue, Jan 2 | vs | Tampa Bay Lightning | TSN3 | W 4-2 |
| Thu, Jan 4 | @ | San Jose Sharks | TSN3 | W 2-1 |
| Fri, Jan 5 | @ | Anaheim Ducks | TVAS, TSN3 | W 3-1 |
| Sun, Jan 7 | @ | ARI | TSN3 | W 6-2 |
| Tue, Jan 9 | vs |   Columbus Blue Jackets | TSN3 | W 5-0 |
| Thu, Jan 11 | vs | Chicago Blackhawks | TSN3 | W 2-1 |
| Sat, Jan 13 | vs |   Philadelphia Flyers | CITY | L 0-2 |
| Tue, Jan 16 | vs |   New York Islanders | TSN3 | W 4-2 |
| Sat, Jan 20 | @ |   Ottawa Senators | CBC, SN, TVAS | W 2-1 (OT) |
| Mon, Jan 22 | @ | Boston Bruins | SN, TVAS | L 1-4 |
| Wed, Jan 24 | @ |   Toronto Maple Leafs | SN, TVAS | OTL 0-1 (OT) |
| Sat, Jan 27 | vs | Toronto Maple Leafs | SN | L 2-4 |
| Tue, Feb 6 | @ |   Pittsburgh Penguins | TSN3 | L 0-3 |
| Thu, Feb 8 | @ | Philadelphia Flyers | TSN3 | L 1-4 |
| Sat, Feb 10 | vs | Pittsburgh Penguins | SNW, CITY | W 2-1 |
| Wed, Feb 14 | vs | San Jose Sharks | SN | W 1-0 |
| Sat, Feb 17 | @ |   Vancouver Canucks | CBC, SN, CITY | W 4-2 |
| Mon, Feb 19 | @ | Calgary Flames | TSN3, SNW | L 3-6 |
| Tue, Feb 20 | vs | Minnesota Wild | TSN3 | W 6-3 |
| Fri, Feb 23 | @ | Chicago Blackhawks | TSN3 | W 3-2 (OT) |
| Sun, Feb 25 | vs | ARI | TSN3 | W 4-3 (OT) |
| Tue, Feb 27 | vs | St. Louis Blues | TSN3 | W 4-2 |
| Thu, Feb 29 | @ | Dallas Stars | TSN3 | L 1-4 |
| Sat, Mar 2 | @ | Carolina Hurricanes | TSN3 · NHLN(US) | W 5-3 |
| Sun, Mar 3 | @ | Buffalo Sabres | TSN3 · NHLN(US) | W 5-2 |
| Tue, Mar 5 | vs |   Seattle Kraken | TSN3 | L 3-4 |
| Fri, Mar 8 | @ | Seattle Kraken | TSN3 | W 3-0 |
| Sat, Mar 9 | @ | Vancouver Canucks | CBC, SN, SN1, TVAS2, CITY | L 0-5 |
| Mon, Mar 11 | vs |   Washington Capitals | SN, TVAS-D | W 3-0 |
| Wed, Mar 13 | vs | Nashville Predators | SN | L 2-4 |
| Fri, Mar 15 | vs | Anaheim Ducks | TSN3 | W 6-0 |
| Sun, Mar 17 | @ | Columbus Blue Jackets | TSN3 | W 6-1 |
| Tue, Mar 19 | @ | New York Rangers | TSN3 | W 4-2 |
| Thu, Mar 21 | @ | New Jersey Devils | TSN3 | L 1-4 |
| Sat, Mar 23 | @ | New York Islanders | TSN3 | L 3-6 |
| Sun, Mar 24 | @ | Washington Capitals | TSN3 · NHLN(US) | L 0-3 |
| Tue, Mar 26 | vs | Edmonton Oilers | TSN3, SNW | OTL 3-4 (OT) |
| Thu, Mar 28 | vs | Vegas Golden Knights | TSN3 | L 1-4 |
| Sat, Mar 30 | vs | Ottawa Senators | SNW, CITY | L 2-3 |
| Mon, Apr 1 | vs | Los Angeles Kings | TVAS, TSN3 | W 4-3 |
| Thu, Apr 4 | vs | Calgary Flames | TSN3, SNW | W 5-2 |
| Sat, Apr 6 | @ | Minnesota Wild | TSN3 | W 4-2 |
| Tue, Apr 9 | @ | Nashville Predators | TSN3 | W 4-3 (OT) |
| Thu, Apr 11 | @ | Dallas Stars | TSN3 | W 3-0 |
| Sat, Apr 13 | @ | Colorado Avalanche | TSN3 | W 7-0 |
| Tue, Apr 16 | vs | Seattle Kraken | TSN3 | W 4-3 |
| Thu, Apr 18 | vs | Vancouver Canucks | TVAS, TSN3, SNP | W 4-2 |
| Sun, Apr 21 | vs | Colorado Avalanche | CBC, SN, TVAS · ESPN2(US) | W 7-6 |
| Tue, Apr 23 | vs | Colorado Avalanche | CBC, TVAS · ESPN(US) | L 2-5 |
| Fri, Apr 26 | @ | Colorado Avalanche | CBC, TVAS · TNT, truTV, MAX(US) | L 2-6 |
| Sun, Apr 28 | @ | Colorado Avalanche | SN, SN360, TVAS · TNT, truTV, MAX(US) | L 1-5 |
| Tue, Apr 30 | vs | Colorado Avalanche | SNW, CBC, TVAS · ESPN(US) | L 3-6 |
