| Fri, Oct 4 | @ |   Buffalo Sabres | NHLN, MSGSN, MSG-B | W 4-1 |
| Sat, Oct 5 | vs | Buffalo Sabres | NHLN, MSGSN, MSG-B | W 3-1 |
| Thu, Oct 10 | vs |   Toronto Maple Leafs | ESPN+, MSG | L 2-4 |
| Sat, Oct 12 | @ |   Washington Capitals | ESPN+, MSGSN, MNMT | W 5-3 |
| Mon, Oct 14 | vs |   Utah Mammoth | ESPN+, MSGSN, Utah16 | W 3-0 |
| Tue, Oct 15 | @ |   Carolina Hurricanes | ESPN+, MSGSN, BSSO | L 2-4 |
| Thu, Oct 17 | @ |   Ottawa Senators | ESPN+, MSG | W 3-1 |
| Sat, Oct 19 | vs | Washington Capitals | ESPN+, MSGSN2, MNMT | OTL 5-6 (OT) |
| Tue, Oct 22 | vs |   Tampa Bay Lightning | ESPN+, MSGSN, FDSNSUN | L 5-8 |
| Thu, Oct 24 | @ |   Detroit Red Wings | ESPN+, MSGSN, FDSNDET | L 3-5 |
| Fri, Oct 25 | vs |   New York Islanders | ESPN+, MSGSN, MSGSN2 | OTL 3-4 (OT) |
| Sun, Oct 27 | vs |   Anaheim Ducks | ESPN+, Victory+, MSGSN, KCOP-13 | W 6-2 |
| Wed, Oct 30 | @ |   Vancouver Canucks | ESPN+, MSGSN | W 6-0 |
| Fri, Nov 1 | @ |   Calgary Flames | ESPN+, MSGSN2 | L 0-3 |
| Mon, Nov 4 | @ |   Edmonton Oilers | NHLN, MSGSN | W 3-0 |
| Thu, Nov 7 | vs |   Montreal Canadiens | ESPN+, MSGSN | W 5-3 |
| Sat, Nov 9 | @ | New York Islanders | ESPN+, MSGSN2, MSGSN | W 4-3 (OT) |
| Sun, Nov 10 | vs |   San Jose Sharks | ESPN+, MSGSN, NBCSCA | L 0-1 |
| Tue, Nov 12 | @ |   Florida Panthers | ESPN+, HULU | W 4-1 |
| Thu, Nov 14 | @ | Florida Panthers | ESPN+, MSGSN, SCRIPPS | W 6-2 |
| Sat, Nov 16 | @ | Tampa Bay Lightning | ESPN+, MSG, FDSNSUN | L 0-4 |
| Thu, Nov 21 | vs | Carolina Hurricanes | ESPN+, MSGSN, FDSNSO | W 4-2 |
| Sat, Nov 23 | @ | Washington Capitals | ESPN+, MSGSN2, MNMT | W 3-2 |
| Mon, Nov 25 | vs |   Nashville Predators | ESPN+, MSGSN, FDSNSO | W 5-2 |
| Wed, Nov 27 | vs |   St. Louis Blues | ESPN+, MSGSN2, FDSNMW | L 0-3 |
| Fri, Nov 29 | @ | Detroit Red Wings | ESPN+, MSGSN, FDSNDET | W 5-4 |
| Sat, Nov 30 | vs | Washington Capitals | ESPN+, MSG, MNMT | L 5-6 |
| Mon, Dec 2 | @ |   New York Rangers | NHLN, MSGSN, MSG | W 5-1 |
| Fri, Dec 6 | vs |   Seattle Kraken | ESPN+, MSGSN, KHN/Prime, KING 5, KONG | W 3-2 |
| Sun, Dec 8 | vs |   Colorado Avalanche | NHLN, MSG, ALT2 | L 0-4 |
| Tue, Dec 10 | vs | Toronto Maple Leafs | ESPN+, HULU | OTL 1-2 (OT) |
| Thu, Dec 12 | vs |   Los Angeles Kings | ESPN+, MSG, FDSNW | W 3-1 |
| Sat, Dec 14 | vs |   Chicago Blackhawks | NHLN, MSGSN, CHSN | W 4-1 |
| Tue, Dec 17 | @ | St. Louis Blues | ESPN+, MSGSN, FDSNMW | W 4-1 |
| Thu, Dec 19 | @ |   Columbus Blue Jackets | ESPN+, MSGSN, FDSNOH | L 2-4 |
| Sat, Dec 21 | vs |   Pittsburgh Penguins | ESPN+, MSGSN, SN-PIT | W 3-0 |
| Mon, Dec 23 | vs | New York Rangers | ESPN+, MSGSN, MSG | W 5-0 |
| Fri, Dec 27 | vs | Carolina Hurricanes | ESPN+, MSGSN, FDSNSO | W 4-2 |
| Sat, Dec 28 | @ | Carolina Hurricanes | ESPN+, MSGSN2, FDSNSO | L 2-5 |
| Tue, Dec 31 | @ | Anaheim Ducks | ESPN+, Victory+, MSGSN | L 2-3 |
| Wed, Jan 1 | @ | Los Angeles Kings | NHLN, MSGSN, FDSNW | L 0-3 |
| Sat, Jan 4 | @ | San Jose Sharks | ESPN+, MSGSN, NBCSCA | L 2-3 |
| Mon, Jan 6 | @ | Seattle Kraken | ESPN+, MSGSN, KHN/Prime, KONG | W 3-2 |
| Thu, Jan 9 | @ | New York Rangers | ESPN+, MSGSN, MSG | OTL 2-3 (OT) |
| Sat, Jan 11 | vs | Tampa Bay Lightning | ESPN+, MSGSN, FDSNSUN | W 3-2 (OT) |
| Tue, Jan 14 | vs | Florida Panthers | ESPN+, HULU | OTL 1-2 (SO) |
| Thu, Jan 16 | @ | Toronto Maple Leafs | ESPN+, MSGSN2 | OTL 3-4 (OT) |
| Sat, Jan 18 | vs |   Philadelphia Flyers | NHLN, MSGSN, NBCSP | L 1-3 |
| Sun, Jan 19 | vs | Ottawa Senators | NHLN, MSGSN | L 1-2 |
| Wed, Jan 22 | vs |   Boston Bruins | NHLN, MSGSN, NESN | W 5-1 |
| Sat, Jan 25 | @ | Montreal Canadiens | NHLN, MSGSN2 | W 4-3 (OT) |
| Mon, Jan 27 | @ | Philadelphia Flyers | ESPN+, MSGSN, NBCSP | L 2-4 |
| Wed, Jan 29 | vs | Philadelphia Flyers | TNT, truTV, MAX | W 5-0 |
| Sun, Feb 2 | @ | Buffalo Sabres | ESPN+, MSGSN, MSG-B | L 3-4 |
| Tue, Feb 4 | @ | Pittsburgh Penguins | ESPN+, MSGSN2, SN-PIT | W 3-2 (SO) |
| Thu, Feb 6 | vs |   Vegas Golden Knights | ESPN+, MSGSN, SCRIPPS | L 1-3 |
| Sat, Feb 8 | @ | Montreal Canadiens | ESPN+, MSGSN | W 4-0 |
| Sat, Feb 22 | vs |   Dallas Stars | ESPN+, Victory+, MSGSN | L 2-4 |
| Sun, Feb 23 | @ | Nashville Predators | NHLN, MSG, FDSNSO | W 5-0 |
| Wed, Feb 26 | @ | Colorado Avalanche | ESPN+, MSGSN, ALT, KTVD | L 1-5 |
| Sat, Mar 1 | @ | Utah Mammoth | ESPN+, MSGSN, Utah16 | W 3-1 |
| Sun, Mar 2 | @ | Vegas Golden Knights | ESPN+, MSGSN, SCRIPPS | L 0-2 |
| Tue, Mar 4 | @ | Dallas Stars | ESPN+, HULU, Disney+ | L 3-4 |
| Fri, Mar 7 | vs |   Winnipeg Jets | ESPN+, MSGSN | L 1-6 |
| Sun, Mar 9 | @ | Philadelphia Flyers | TNT, truTV, MAX | W 3-1 |
| Tue, Mar 11 | vs | Columbus Blue Jackets | ESPN+, MSGSN, FDSNOH | W 5-3 |
| Thu, Mar 13 | vs | Edmonton Oilers | ESPN+, HULU, Disney+ | W 3-2 |
| Sat, Mar 15 | @ | Pittsburgh Penguins | ESPN+, ABC | L 3-7 |
| Mon, Mar 17 | @ | Columbus Blue Jackets | ESPN+, MSGSN, FDSNOH | W 2-1 |
| Thu, Mar 20 | vs | Calgary Flames | ESPN+, MSGSN2 | L 3-5 |
| Sat, Mar 22 | vs | Ottawa Senators | ESPN+, MSGSN2, MSGSN | L 2-3 |
| Mon, Mar 24 | vs | Vancouver Canucks | ESPN+, HULU, Disney+ | OTL 3-4 (SO) |
| Wed, Mar 26 | @ | Chicago Blackhawks | TNT, truTV, MAX, CHSN | W 5-3 |
| Fri, Mar 28 | @ | Winnipeg Jets | ESPN+, MSGSN | L 0-4 |
| Sat, Mar 29 | @ |   Minnesota Wild | ESPN+, MSGSN, FDSNNO, FDSNWIX | W 5-2 |
| Mon, Mar 31 | vs | Minnesota Wild | NHLN, MSGSN, FDSNNO, FDSNWIX | W 3-2 (SO) |
| Sat, Apr 5 | vs | New York Rangers | ESPN+, ABC | W 4-0 |
| Tue, Apr 8 | vs | Boston Bruins | ESPN+, MSG, NESN | L 2-7 |
| Fri, Apr 11 | vs | Pittsburgh Penguins | NHLN, MSGSN, SN-PIT | L 2-4 |
| Sun, Apr 13 | vs | New York Islanders | TNT, truTV, MAX | L 0-1 |
| Tue, Apr 15 | @ | Boston Bruins | ESPN+, MSGSN, NESN | W 5-4 (OT) |
| Wed, Apr 16 | vs | Detroit Red Wings | TNT, truTV, MAX, FDSNDET | L 2-5 |
| Sun, Apr 20 | @ | Carolina Hurricanes | ESPN, MSGSN, FDSNSO | L 1-4 |
| Tue, Apr 22 | @ | Carolina Hurricanes | ESPN, MSGSN, FDSNSO | L 1-3 |
| Fri, Apr 25 | vs | Carolina Hurricanes | TBS, MAX, MSGSN, FDSNSO | W 3-2 (OT) |
| Sun, Apr 27 | vs | Carolina Hurricanes | TBS, truTV, MAX, MSGSN, FDSNSO | L 2-5 |
| Tue, Apr 29 | @ | Carolina Hurricanes | TBS, MAX, MSGSN, FDSNSO | OTL 4-5 (OT) |
