| Tue, Oct 7 | vs |   Chicago Blackhawks | ESPN | W 3-2 |
| Thu, Oct 9 | vs |   Philadelphia Flyers | ESPN+, SCRIPPS, NBCSP | W 2-1 |
| Sat, Oct 11 | vs |   Ottawa Senators | ESPN+, SCRIPPS | W 6-2 |
| Mon, Oct 13 | @ | Philadelphia Flyers | ESPN+, SCRIPPS, NBCSP | L 2-5 |
| Wed, Oct 15 | @ |   Detroit Red Wings | HBO MAX, TNT, truTV | L 1-4 |
| Thu, Oct 16 | @ |   New Jersey Devils | ESPN+, SCRIPPS, MSGSN | L 1-3 |
| Sat, Oct 18 | @ |   Buffalo Sabres | ESPN+, SCRIPPS, MSG-B | L 0-3 |
| Tue, Oct 21 | @ |   Boston Bruins | ESPN | W 4-3 |
| Thu, Oct 23 | vs |   Pittsburgh Penguins | ESPN+, SCRIPPS, SN-PIT | L 3-5 |
| Sat, Oct 25 | vs |   Vegas Golden Knights | ESPN+, SCRIPPS, SCRIPPS | W 3-0 |
| Tue, Oct 28 | vs |   Anaheim Ducks | ESPN+, Victory+, SCRIPPS, KCOP-13 | OTL 2-3 (SO) |
| Sat, Nov 1 | vs |   Dallas Stars | ESPN+, Victory+, SCRIPPS | W 4-3 (SO) |
| Tue, Nov 4 | @ | Anaheim Ducks | ESPN+, Victory+, SCRIPPS, KCOP-13 | L 3-7 |
| Thu, Nov 6 | @ |   Los Angeles Kings | ESPN+, HULU | W 5-2 |
| Sat, Nov 8 | @ |   San Jose Sharks | ESPN+, SCRIPPS, NBCSCA | L 1-3 |
| Mon, Nov 10 | @ | Vegas Golden Knights | ESPN+, SCRIPPS, SCRIPPS | W 3-2 |
| Thu, Nov 13 | vs |   Washington Capitals | ESPN+, SCRIPPS, MNMT | W 6-3 |
| Sat, Nov 15 | vs |   Tampa Bay Lightning | ESPN+, SCRIPPS, The Spot | L 1-3 |
| Mon, Nov 17 | vs |   Vancouver Canucks | ESPN+, SCRIPPS | W 8-5 |
| Thu, Nov 20 | vs | New Jersey Devils | ESPN+, SCRIPPS, MSGSN | W 1-0 |
| Sat, Nov 22 | vs |   Edmonton Oilers | NHLN, SCRIPPS | L 3-6 |
| Mon, Nov 24 | @ |   Nashville Predators | ESPN+, SCRIPPS, FDSNSO | W 8-3 |
| Wed, Nov 26 | vs | Philadelphia Flyers | ESPN+, SCRIPPS, NBCSP | L 2-4 |
| Fri, Nov 28 | vs |   Calgary Flames | ESPN+, SCRIPPS | L 3-5 |
| Tue, Dec 2 | vs |   Toronto Maple Leafs | ESPN+, HULU | L 1-4 |
| Thu, Dec 4 | vs | Nashville Predators | ESPN+, SCRIPPS, FDSNSO | OTL 1-2 (OT) |
| Sat, Dec 6 | vs |   Columbus Blue Jackets | ESPN+, SCRIPPS, FDSNOH | W 7-6 (OT) |
| Sun, Dec 7 | vs |   New York Islanders | ESPN+, SCRIPPS, MSGSN | W 4-1 |
| Wed, Dec 10 | @ |   Utah Mammoth | ESPN+, SCRIPPS, Utah16 | W 4-3 |
| Thu, Dec 11 | @ |   Colorado Avalanche | ESPN | L 2-6 |
| Sat, Dec 13 | @ | Dallas Stars | ESPN+, Victory+, SCRIPPS | W 4-0 |
| Mon, Dec 15 | @ | Tampa Bay Lightning | NHLN, SCRIPPS, The Spot | W 5-2 |
| Wed, Dec 17 | vs | Los Angeles Kings | ESPN+, SCRIPPS, FDSNW | W 3-2 |
| Fri, Dec 19 | vs |   Carolina Hurricanes | ESPN+, SCRIPPS, FDSNSO | W 4-3 (SO) |
| Sat, Dec 20 | vs |   St. Louis Blues | ESPN+, SCRIPPS, FDSNMW | L 2-6 |
| Tue, Dec 23 | @ | Carolina Hurricanes | ESPN+, SCRIPPS, FDSNSO | W 5-2 |
| Sat, Dec 27 | vs | Tampa Bay Lightning | ESPN+, SCRIPPS, The Spot | L 2-4 |
| Mon, Dec 29 | vs | Washington Capitals | ESPN+, SCRIPPS, MNMT | W 5-3 |
| Tue, Dec 30 | vs |   Montreal Canadiens | ESPN+, SCRIPPS | OTL 2-3 (OT) |
| Fri, Jan 2 | vs |   New York Rangers | HBO MAX, TNT, truTV | L 1-5 |
| Sun, Jan 4 | vs | Colorado Avalanche | ESPN+, SCRIPPS, ALT | W 2-1 |
| Tue, Jan 6 | @ | Toronto Maple Leafs | HBO MAX, TNT | L 1-4 |
| Thu, Jan 8 | @ | Montreal Canadiens | ESPN+, SCRIPPS | L 2-6 |
| Sat, Jan 10 | @ | Ottawa Senators | NHLN, SCRIPPS | W 3-2 |
| Mon, Jan 12 | @ | Buffalo Sabres | ESPN+, SCRIPPS, MSG-B | W 4-3 |
| Fri, Jan 16 | @ | Carolina Hurricanes | ESPN+, SCRIPPS, FDSNSO | L 1-9 |
| Sat, Jan 17 | @ | Washington Capitals | ESPN+, SCRIPPS, MNMT | W 5-2 |
| Mon, Jan 19 | vs | San Jose Sharks | ESPN+, SCRIPPS, NBCSCA | L 1-4 |
| Thu, Jan 22 | @ |   Winnipeg Jets | ESPN+, SCRIPPS | W 2-1 (SO) |
| Sat, Jan 24 | @ |   Minnesota Wild | ESPN+, SCRIPPS, FDSNNO, FDSNWI | W 4-3 (OT) |
| Sun, Jan 25 | @ | Chicago Blackhawks | NHLN, SCRIPPS, CHSN | W 5-1 |
| Tue, Jan 27 | vs | Utah Mammoth | ESPN+, SCRIPPS, Utah16 | L 3-4 |
| Thu, Jan 29 | @ | St. Louis Blues | ESPN+, SCRIPPS, FDSNMW | L 4-5 |
| Sat, Jan 31 | vs | Winnipeg Jets | ESPN+, SCRIPPS | L 1-2 |
| Mon, Feb 2 | vs | Buffalo Sabres | ESPN+, SCRIPPS, MSG-B | L 3-5 |
| Wed, Feb 4 | vs | Boston Bruins | HBO MAX, TNT | W 5-4 (SO) |
| Thu, Feb 5 | @ | Tampa Bay Lightning | ESPN+, HULU | L 1-6 |
| Thu, Feb 26 | vs | Toronto Maple Leafs | ESPN+, SCRIPPS | W 5-1 |
| Fri, Feb 27 | vs | Buffalo Sabres | ESPN+, SCRIPPS, MSG-B | L 2-3 |
| Sun, Mar 1 | @ | New York Islanders | ESPN | L 4-5 |
| Tue, Mar 3 | @ | New Jersey Devils | HBO MAX, TNT, SCRIPPS | L 1-5 |
| Thu, Mar 5 | @ | Columbus Blue Jackets | ESPN+, SCRIPPS, FDSNOH | L 2-4 |
| Fri, Mar 6 | @ | Detroit Red Wings | NHLN, SCRIPPS, FDSNDET | W 3-1 |
| Tue, Mar 10 | vs | Detroit Red Wings | ESPN+, SCRIPPS, FDSNDET | W 4-3 |
| Thu, Mar 12 | vs | Columbus Blue Jackets | ESPN+, SCRIPPS, FDSNOH | W 2-1 (OT) |
| Sun, Mar 15 | @ |   Seattle Kraken | ESPN+, SCRIPPS, KHN/Prime, KONG | L 2-6 |
| Tue, Mar 17 | @ | Vancouver Canucks | ESPN+, SCRIPPS | L 2-5 |
| Thu, Mar 19 | @ | Edmonton Oilers | ESPN+, SCRIPPS | W 4-0 |
| Fri, Mar 20 | @ | Calgary Flames | ESPN+, SCRIPPS | L 1-4 |
| Tue, Mar 24 | vs | Seattle Kraken | ESPN+, SCRIPPS, KHN/Prime, KING 5, KONG | W 5-4 (SO) |
| Thu, Mar 26 | vs | Minnesota Wild | ESPN | L 2-3 |
| Sat, Mar 28 | @ | New York Islanders | ESPN+, SCRIPPS, MSGSN | L 2-5 |
| Sun, Mar 29 | @ | New York Rangers | NHLN, SCRIPPS, MSG | L 1-3 |
| Tue, Mar 31 | vs | Ottawa Senators | ESPN+, SCRIPPS | W 6-3 |
| Thu, Apr 2 | vs | Boston Bruins | ESPN+, SCRIPPS, NESN | W 2-1 |
| Sat, Apr 4 | @ | Pittsburgh Penguins | ESPN+, SCRIPPS, SN-PIT | L 4-9 |
| Sun, Apr 5 | @ | Pittsburgh Penguins | ESPN+, SCRIPPS, SN-PIT | L 2-5 |
| Tue, Apr 7 | @ | Montreal Canadiens | ESPN+, SCRIPPS | OTL 3-4 (SO) |
| Thu, Apr 9 | @ | Ottawa Senators | ESPN+, SCRIPPS | L 1-5 |
| Sat, Apr 11 | @ | Toronto Maple Leafs | ESPN+, SCRIPPS | W 6-2 |
| Mon, Apr 13 | vs | New York Rangers | ESPN+, SCRIPPS, MSG | W 3-2 |
| Wed, Apr 15 | vs | Detroit Red Wings | ESPN+, SCRIPPS, FDSNDET | W 8-1 |
